Nkọwa dị mkpirikpi:
Nọmba CAS: 7177-48-2
Usoro ihe omimi: C16H25N3O7S
arọ molekụla: 403.45
Ọdịdị kemịkal:
| Ozi bụ isi | |
| Aha ngwaahịa | Ampicillin |
| Ọkwa | Ọkwa ọgwụ |
| Ọdịdị | Ọcha ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ ọcha, ntụ ntụ kristal |
| Nyocha | |
| Ndụ nchekwa | afọ 2 |
| Nkwakọ ngwaahịa | 25kg / agba |
| Ọnọdụ | echekwara na jụụ na nkụ |
Nkọwa
Dị ka otu penicillin nke ọgwụ nje beta-lactam, Ampicillin bụ penicillin nke mbụ sara mbara, nke nwere ọrụ in vitro megide nje gram-positive na gram-negative aerobic na anaerobic bacteria, nke a na-ejikarị egbochi na ịgwọ ọrịa nje nke akụkụ okuku ume, urinary tract. traktị, ntị etiti, sinuses, afo na eriri afọ, eriri afo, na akụrụ, wdg. nke nje bacteria nwere ike ịkpata. A na-ejikwa ya na-agwọ gonorrhea na-enweghị mgbagwoju anya, meningitis, endocarditis salmonellosis, na ọrịa ndị ọzọ dị njọ site n'ọnụ, ntụtụ intramuscular ma ọ bụ ntinye n'ime eriri afọ. Dị ka ọgwụ nje niile, ọ naghị adị irè maka ọgwụgwọ ọrịa nje.
Ampicillin na-arụ ọrụ site na igbu nje bacteria ma ọ bụ gbochie uto ha. Mgbe ịbanye n'ime nje bacteria Gram-positive na Gram-negative, ọ na-eme dị ka onye na-adịghị agbanwe agbanwe nke enzyme transpeptidase nke nje bacteria chọrọ iji mee mgbidi cell, nke na-ebute nkwụsị nke mgbidi cell na-emecha na-eduga na cell lysis.
Ọrụ antimicrobial
Ampicillin adịchaghị arụ ọrụ karịa benzylpenicillin megide ọtụtụ nje bacteria nwere gram ma ọ na-arụsi ọrụ ike megide E. faecalis. MRSA na ụdị Str. oyi oyi nwere mbelata ohere nke benzylpenicillin na-eguzogide ọgwụ. Ọtụtụ ndị otu D streptococci, anaerobic Gram-positive cocci na bacilli, gụnyere L. monocytogenes, Actinomyces spp. na Arachnia spp., nwere ike ime ya. Mycobacteria na nocardia na-eguzogide ọgwụ.
Ampicillin nwere ọrụ yiri ya na benzylpenicillin megide N. gonorrheae, N. meningitidis na Mor. catarrhalis. Ọ na-arụsi ọrụ ike ugboro 2-8 karịa benzylpenicillin megide influenzae H. na ọtụtụ Enterobacteriaceae, mana ụdị nke na-emepụta β-lactamase na-eguzogide ọgwụ. Pseudomonas spp. na-eguzogide ọgwụ, ma Bordetella, Brucella, Legionella na Campylobacter spp. na-adịkarị mfe. Ụfọdụ anaerobes gram-adịghị mma dị ka Prevotella melaninogenica na Fusobacterium spp. dị mfe, ma B. fragilis na-eguzogide ọgwụ, dị ka mycoplasmas na rickettsiae.
Ọrụ megide molekụla klas A β-lactamase na-emepụta ụdị staphylococci, gonococci, H. influenzae, Mor. catarrhalis, ụfọdụ Enterobacteriaceae na B. fragilis na-abawanye site na ọnụnọ nke β-lactamase inhibitors, kpọmkwem clavulanic acid.
Ọrụ nje nje ya yiri nke benzylpenicillin. Mmekọrịta nje bacteria na-eme na aminoglycosides megide E. faecalis na ọtụtụ enterobacteria, yana mecillinam megide ọtụtụ enterobacteria na-eguzogide ampicillin.
