Ceftriaxone sodium

Ceftriaxone sodium bụ β-lactamase-eguzogide ọgwụ cephalosporin nwere ogologo ndụ ọbara ọbara. Ihe abụọ na-enye aka na ogologo oge ọrụ nke ceftriaxone: njikọ protein dị elu na plasma na mwepụ nke ngwa ngwa. A na-ewepụ Ceftriaxone na bile na mmamịrị. Probenecid anaghị emetụta mpụta mmamịrị ya. N'agbanyeghị oke nkesa ya dị ala, ọ na-erute mmiri cerebrospinal na mkpokọta nke dị irè na meningitis. Ahụrụ ọgwụ pharmacokinetic na-adịghị n'ịntanetị.
Ceftriaxone nwere sistemu heterocyclic acid nke ukwuu na otu 3-thiomethyl. Ekwenyere na sistemụ mgbanaka dioxotriazine a na-adịghị ahụkebe na-enye ndị na-ahụ maka ọgwụ a pụrụ iche. Ejikọla Ceftriaxone na sonographically achọpụtara “sludge,” ma ọ bụ pseudolithiasis, na gallbladder na bile duct nkịtị. Mgbaàmà nke cholecystitis nwere ike ime n'ime ndị ọrịa nwere ike ime ya, ọkachasị ndị a na-eme ogologo oge ma ọ bụ nke dị elu na ọgwụgwọ ceftriaxone. Achọpụtara onye kpatara ya dị ka calcium chelate.
Ceftriaxone na-egosiputa mmetụta nje antibacterial sara mbara nke ukwuu megide ma gram-positive na gram-negativeorganisms. Ọ na-eguzogide nke ukwuu n'ọtụtụ chromosomal na plasmid-mediated β-lactamase. Ọrụ nke ceftriaxone megide Enterobacter, Citrobacter, Serratia, indole-positiveProteus, na Pseudomonas spp. na-adọrọ mmasị karịsịa. Ọ dịkwa irè na ọgwụgwọ nke ampicillin na-eguzogide gonorrheaand H. influenzae ọrịa ma n'ozuzu obere activation karịa cefotaxime megide Gram-positive bacteria na B.fragilis.