环维生物

Ụlọ ọrụ HUANWEI BIOTECH

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Clindamycin Phosphate Raw Materials

Nkọwa dị mkpirikpi:

Nọmba CAS:24729-96-2

Usoro ihe omimi:C18H34ClN2O8PS

arọ molekụla: 504.96

Ọdịdị kemịkal:


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  • Nkọwa ngwaahịa

    Mkpado ngwaahịa

    Ozi bụ isi
    Aha ngwaahịa Clindamycin phosphate
    Ọkwa Ọkwa ọgwụ
    Ọdịdị ọcha ntụ ntụ
    Nyocha 95%
    Ndụ nchekwa afọ 2
    Nkwakọ ngwaahịa 25kg / agba
    Ọnọdụ Kwụsie ike, mana chekwaa ya nke ọma. Na-ekwekọghị na ndị ọrụ oxidizing siri ike, calcium gluconate, barbiturates, magnesium sulfate, phenytoin, vitamin B otu sodium.

    Nkọwa

    Clindamycin phosphate bụ ester nke na-agbaze mmiri nke ọgwụ nje semisynthetic nke 7 (S) -chloro nnọchi nke otu 7 (R) -hydroxyl nke ọgwụ nje nne na nna, lincomycin mepụtara. Nke a bụ lincomycin (lincosamide). O nwere mmetụta bacteriostatic bụ isi megide aerobes gram-positive yana ọtụtụ ụdị anaerobicbacteria. Ọ bụ ọgwụ nje dị n'elu nke a na-eji agwọ ọrịa. Ndị a nwere ike ịgụnye ọrịa nke traktị iku ume, septicaemia, peritonitis na ọrịa ọkpụkpụ. A na-ejikwa ya agwọ oke otutu ma ọ bụ nke siri ike.

    Jiri

    A na-eji Clindamycin phosphate naanị n'elu elu ma ọ bụ yana njikọ benzoyl peroxide na ọgwụgwọ nke ihe otutu vulgaris na-afụ ụfụ. N'ịtụle uru dị na ọgwụgwọ clindamycin dị n'elu, enwere ike ịnwe mmetụta ọjọọ GI metụtara ọgwụ ahụ. Ọgwụgwọ nke ihe otutu vulgaris ga-abụrịrị onye n'otu n'otu ma gbanwee ugboro ugboro dabere na ụdị ọnya ọnya nke na-ebutekarị yana nzaghachi ọgwụgwọ. Ọgwụ mgbochi ọrịa ndị dị n'elu, gụnyere clindamycin, na-adịkarị mma n'ịgwọ ihe otutu na-akpasu iwe dị nro ma na-agafeghị oke. Otú ọ dị, iji ọgwụ nje eme ihe dị ka monotherapy nwere ike iduga nguzogide nje bacteria; Ejikọtara nguzogide a na mbelata nrụpụta ụlọ ọgwụ. Topical clindamycin bara uru karịsịa mgbe ejiri benzoyl peroxide ma ọ bụ retinoids top. Nsonaazụ nke ọmụmụ ụlọ ọgwụ na-egosi na ọgwụgwọ njikọta na-ebute mbelata mkpokọta ọnya nke 50-70%.

    Clindamycin 2-phosphate bụ aa nnu nke clincamycin, lincosamide ọkara synthetic. A na-akwadebe nnu site na phosphorylation nhọrọ nke 2-hydroxy moiety nke sugar clindamycin. Iwebata phosphates na-enye mma solubility maka usoro injectable. Dị ka ndị ọzọ nọ na ezinụlọ lincosamide, clindamycin 2-phosphate bụ ọgwụ nje dị iche iche na-arụ ọrụ megide nje anaerobic na protozoans. Clindamycin na-arụ ọrụ site na ijikọ na 23S ribosomal subunit, na-egbochi njikọ protein.


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