Mbadamba ụrọ folate (Folic acid, vitamin B9)

Mbadamba ụrọ folate (Folic Acid, Vit B9) onyonyo egosipụtara

Nkọwa dị mkpirikpi:

Round,Oval,Oblong,Triangle,Diamond na ụfọdụ ụdị pụrụ iche dị.

asambodo

Nkọwa ngwaahịa

Mkpado ngwaahịa

Ozi bụ isi
Aha ngwaahịa	Mbadamba ụrọ folate
Aha ndị ọzọ	Mbadamba ụrọ folic acid, mbadamba ụrọ folic arụ ọrụ, mbadamba folic acid na-arụ ọrụ, wdg.
Ọkwa	Nri nri
Ọdịdị	Dị ka ndị ahịa 'chọrọ Round,Oval,Oblong,Triangle,Diamond na ụfọdụ ụdị pụrụ iche dị.
Ndụ nchekwa	2-3 afọ, dabere na ọnọdụ ụlọ ahịa
Nkwakọ ngwaahịa	Nnukwu, karama, ngwugwu ọnya ma ọ bụ ihe ndị ahịa chọrọ
Ọnọdụ	Chekwaa n'ime akpa siri ike, nke echedoro na ìhè.

Nkọwa

Mmetụta nke folic acid na ntule na-egosipụtakarị na akụkụ ndị a: isonye na metabolism nke mkpụrụ ndụ ihe nketa na protein; na-emetụta arụmọrụ ọmụmụ anụmanụ; na-emetụta secretion nke anụ ụlọ pancreas; na-akwalite uto ụmụ anụmanụ; na imeziwanye ihe mgbochi ahụ.

Methyltetrahydrofolate na-ezokarị aka na 5-methyltetrahydrofolate, nke nwere ọrụ nke na-edozi ahụ na ịgbakwunye folic acid. 5-Methyltetrahydrofolate bụ ihe nwere ọrụ na-arụ ọrụ nke na-agbanwe site na folic acid site na usoro mmeghachi omume biochemical na ahụ mmadụ. Ahụ nwere ike iji ya mee ihe n'ụzọ dị iche iche nke metabolic iji nọgide na-arụ ọrụ nkịtị nke ahụ, si otú ahụ na-ekere òkè n'ịkwalite ahụ.

Ọrụ

Folic acid bụ ụdị vitamin B, nke a makwaara dị ka pteroylglutamic acid. 5-methyltetrahydrofolate bụ nzọụkwụ ikpeazụ na metabolism na usoro mgbanwe nke folic acid n'ime ahụ. N'ihi ọrụ ya na-arụ ọrụ, a na-akpọkwa ya ọrụ. Folic acid bụ ihe mejupụtara folic acid n'ime ahụ.

N'ihi na usoro ihe omimi nke 5-methyltetrahydrofolate nwere ike ịmịnye ya ozugbo na-enweghị usoro ntụgharị metabolic gbagwojuru anya, ọ na-adị na sel anụ ahụ. E jiri ya tụnyere folic acid, ọ dị mfe ịgbakwunye ihe oriri maka ahụ, karịsịa maka ndị inyom chọrọ ịkwadebe maka afọ ime na ndị inyom dị ime n'oge ime ime.

Folic acid bụ otu n'ime vitamin ndị dị mkpa maka uto na mmeputakwa nke mkpụrụ ndụ ahụ. Ekike ya ga-emetụta ọrụ physiological nkịtị nke ahụ mmadụ. Ọtụtụ akwụkwọ akụkọ na-akọ na ụkọ folic acid na-emetụta kpọmkwem ntụpọ tube akwara, megaloblastic anaemia, mgbawa egbugbere ọnụ na palate, ịda mbà n'obi, etuto ahụ na ọrịa ndị ọzọ.

Ọkpụkpụ akwara akwara (NTDs)

Neural tube malformations (NTDs) bụ otu ntụpọ na-akpata site na mmechi na-ezughị ezu nke akwara akwara n'oge mmepe embrayo, gụnyere anencephaly, encephalocele, spina bifida, wdg, ma bụrụ otu n'ime ntụpọ nwa ọhụrụ na-ahụkarị. Na 1991, British Medical Research Council kwadoro na nke mbụ na folic acid supplementation tupu ime ime na mgbe ime ime nwere ike igbochi omume nke NTD ma belata ihe omume site na 50-70%. Mmetụta mgbochi nke folic acid na NTDs ka ewerewo dịka otu n'ime nchọpụta ahụike kacha atọ ụtọ na njedebe narị afọ nke 20.

Megaloblastic anaemia (MA)

Megaloblastic anaemia (MA) bụ ụdị anaemia na-akpata site na mmebi na DNA njikọ nke enweghị folic acid ma ọ bụ vitamin B12 kpatara. Ọ na-adịkarị na ụmụ ọhụrụ na ụmụ nwanyị dị ime. Nzụlite nwa ebu n'afọ na-adịkarị chọrọ nnukwu ego nke folic acid n'ime ahụ nne. Ọ bụrụ na ihe nchekwa folic acid agwụla n'oge ime ma ọ bụ n'oge ọmụmụ, megaloblastic anaemia ga-apụta na nwa ebu n'afọ na nne. Mgbe agbakwunyere folic acid, ọrịa ahụ nwere ike ịgbake ngwa ngwa wee gwọọ ya.

Folic acid na mgbawa egbugbere ọnụ na palate

Egbugbere ọnụ na ọnụ ọnụ (Cleft and palate) bụ otu n'ime ntụpọ ọmụmụ a na-ahụkarị. Ihe kpatara mgbawa egbugbere ọnụ na ọnụ ọnụ ka amabeghị. Achọpụtara mgbakwunye folic acid n'oge mmalite ime ime iji gbochie ọmụmụ ụmụaka nwere mgbawa egbugbere ọnụ na ọnụ ọnụ.

Ọrịa ndị ọzọ

Enweghị folic acid nwere ike imerụ ndị nne na ụmụaka nnukwu nsogbu, dị ka ime ọpụpụ na-emekarị, ịmụ nwa akabeghị aka, ịdị arọ nke ịmụ nwa, mgbari afọ nwa na nkwụsị uto. Ọtụtụ akwụkwọ na-akọ na ọrịa Alzheimer, ịda mbà n'obi, na ọrịa akwara ozi n'ime ụmụ amụrụ ọhụrụ na ọnya ụbụrụ ndị ọzọ metụtara ya niile metụtara ụkọ folic acid. Na mgbakwunye, enweghị folic acid nwekwara ike ịkpata etuto (cancer uterine, cancer bronchial, cancer esophageal, cancer colorectal, wdg), gastritis na-adịghị ala ala, colitis, ọrịa obi obi na ọrịa cerebrovascular, yana ọrịa ndị ọzọ dị ka glossitis. eto eto adịghị mma. Ndị okenye na-enwechaghị folic acid ma na-aṅụ oke mmanya nwere ike ịgbanwe nhazi nke mucosa eriri afọ ha.