Nkọwa dị mkpirikpi:
Nọmba CAS: 59-05-2
Usoro ihe omimi: C20H22N8O5
arọ molekụla: 454.45
Ọdịdị kemịkal:
| Ozi bụ isi | |
| Aha ngwaahịa | Methotrexate |
| Ọkwa | ọkwa ọgwụ |
| Ọdịdị | oroma-acha odo odo crystalline ntụ ntụ. |
| Nyocha | 99% |
| Ndụ nchekwa | afọ 2 |
| Nkwakọ ngwaahịa | 25kg / katọn |
| Njirimara | Kwụsie ike, mana ọkụ na-enwe mmetụta na hygroscopic. Ekwekọrịtaghị na acid siri ike, ndị ọrụ oxidizing siri ike. |
| Ọnọdụ | Debe n'ebe gbara ọchịchịrị, ikuku na-adịghị mma, chekwaa na friza, n'okpuru -20 Celsius |
Kedu ihe bụ Methotrexate?
Methotrexate na-enwe mmetụta maka hydrolysis, oxidation na ìhè. Na-adịghị edozi na mmiri. Methotrexate na-emebi emebi na ọnọdụ acidic ma ọ bụ alkaline. Methotrexate ekwekọghị na ihe ndị na-eme ka oxidizing siri ike na acid siri ike.
Methotrexate bụ ọgwụ eji agwọ ọrịa kansa, nke a makwaara dị ka ọgwụ cytotoxic. Iji belata cytotoxicity ya, enwere ike iji ya na calcium leucovorin. A na-eji ya maka ọgwụgwọ ọrịa leukemia nnukwu (nnukwu lymphocytic leukemia), ọrịa ara ara, malignant mole na choriocarcinoma, isi na olu cancer, ọkpụkpụ ọkpụkpụ, leukemia, ọkpụkpụ azụ meningeal infiltration, cancer akpa ume, usoro ọmụmụ cancer, imeju cancer, refractory. psoriasis vulgaris, dermatomyositis, myositis ahụ, ankylosing spondylitis mbufụt, ọrịa Crohn, psoriasis na psoriatic ogbu na nkwonkwo, ọrịa Behcet na autoimmune ọrịa. Methotrexate bụ ihe na-egbochi immunosuppressant na enwere ike iji ya mee ka usoro nke rheumatism dị mfe na-arụ ọrụ nke ọma na ọgwụgwọ synovial mbufụt nke ọrịa ogbu na nkwonkwo na bụ ọgwụ a na-ejikarị eme ihe maka ọgwụgwọ ọrịa rheumatoid.
Ngwa ụlọ ọgwụ
Ọ na-arụ ọrụ nke ọma n'ịgwọ ọrịa leukemia ukwu na-arụ ọrụ nke ọma na ndị ọrịa ụmụaka. Ọ nwere mmetụta dị mma n'ịgwọ choriocarcinoma na ahumachi ọjọọ. Nnukwu nchịkwa dose dị irè n'ịgwọ osteosarcoma, sarcoma anụ ahụ dị nro, ọrịa cancer akpa ume, ọrịa cancer testicular, ọrịa ara ara, na cancer ovarian. Ọ dịkwa irè n'ịgwọ ọrịa kansa isi na olu, ọrịa imeju na ọrịa kansa eriri afọ. Infusion nke akwara akwara nke ngwaahịa a na-arụ ọrụ nke ọma n'ịgwọ ọrịa kansa na olu na ọrịa kansa imeju. Otú ọ dị, a na-ejikarị ya eme ihe maka ọgwụgwọ psoriasis na psoriasis.
