Nkọwa dị mkpirikpi:
Nọmba CAS: 69004-03-1
Usoro ihe omimi: C18H14F3N3O4S
arọ molekụla: 425.38
Ọdịdị kemịkal:
| Ozi bụ isi | |
| Aha ngwaahịa | Toltrazuril |
| CAS Mba. | 69004-03-1 |
| Agba | Ọcha ma ọ bụ ọ fọrọ nke nta ka ọ bụrụ ntụ ntụ crystalline ọcha |
| Ọkwa | Nri ọkwa |
| Nchekwa | Emechiri ya na nkụ, Okpomọkụ ụlọ |
| Ndụ shelf | afọ 2 |
| Jiri | Ehi, Chicken, Nkịta, Azụ, Ịnyịnya, Ezi |
| ngwugwu | 25kg/drum |
Nkọwa
Toltrazuril (Baycox®, Procox®) bụ ọgwụ triazinon nke nwere nnukwu anticoccidial na antiprotozoalactivity. Ọ bụghị maka azụmahịa na United States, mana ọ dị na mba ndị ọzọ. Ọ na-arụsi ọrụ ike megide ma asexual na mmekọahụ nke coccidia site na igbochi nkewa nke schizonts na microga-mons nuklia na ozu na-akpụ mgbidi nke macrogamont. Ọ nwekwara ike ịba uru na ọgwụgwọ porcinecoccidiosis nke nwa amụrụ ọhụrụ, EPM, na hepatozoonosis canine.
Toltrazuril na isi metabolite ponazuril (toltrazuril sulfone, Marquis) bụ ọgwụ antiprotozoal dabeere na triazine nke nwere ọrụ kpọmkwem megide ọrịa apicomplexan coccidial. Toltrazuril adịghị na United States.
Ngwa nke ngwaahịa
Ezì: E gosipụtara Toltrazuril iji belata ihe ịrịba ama nke coccidiosis na ezì na-enye nwa ara mgbe otu ọnụ 20-30 mg / kg BWdose na-enye 3 ruo 6-dayold pigs (Driesen et al., 1995). E belatara ihe ịrịba ama ụlọ ọgwụ site na 71 ruo 22% nke ezi ndị nọọsụ, na afọ ọsịsa na nsị oocyst na-ebelatakwa site na otu ọgwụgwọ ọnụ. Ngwaahịa akwadoro na-ebu oge iwepụ ụbọchị 77 na United Kingdom.
Ụmụ ehi na ụmụ atụrụ: A na-eji Toltrazuril maka igbochi ihe ịrịba ama ụlọ ọgwụ nke coccidiosis na mbelata coccidia n'ime ụmụ ehi na ụmụ atụrụ dịka otu ọgwụgwọ ọgwụgwọ. Oge mwepụ na United Kingdom bụ ụbọchị 63 na 42 maka ụmụ ehi na ụmụ atụrụ, n'otu n'otu.
Nkịta: Maka hepatozoonosis, toltrazuril na-enye ọnụ na 5 mg / kg BW kwa awa 12 maka ụbọchị 5 ma ọ bụ nye ya ọnụ na 10 mg / kg BW kwa awa 12 ọ bụla maka ụbọchị 10 kpatara mgbaghara nke akara ụlọ ọgwụ na nkịta butere ọrịa n'ime ụbọchị 2-3. Macintire et al., 2001). N'ụzọ dị mwute, ọtụtụ nkịta a na-agwọ ọrịa laghachiri azụ ma mesịa nwụọ site na hepatozoonosis. N'ime ụmụ nkịta nwere Isospora sp. ọrịa, ọgwụgwọ na 0.45 mg emodepside na 9 mg/kg BW toltrazuril (Procox®, Bayer Animal Health) na-ebelata fecal oocyst ọnụ site 91.5-100%. Ọ dịghị ihe dị iche na oge afọ ọsịsa mgbe ọgwụgwọ malitere mgbe mmalite nke mgbaàmà ahụike n'oge ọrịa patent (Altreuther et al., 2011).
Nwamba: N'ime kittens nwere ọrịa Isospora spp., ọgwụgwọ na otu ọnụ nke 0.9 mg emodepside yana 18 mg/kg BW toltrazuril (Procox®, Bayer AnimalHealth) na-ebelata ịwụsa oocyst site na 96.7-100% ma ọ bụrụ na enyere ya n'oge prepatent. oge (Petry et al., 2011).
Ịnyịnya: A na-ejikwa Toltrazuril maka ọgwụgwọ EPM. Ọgwụ a dị mma, ọbụlagodi na oke doses. Usoro ọgwụgwọ akwadoro ugbu a bụ 5-10 mg/kg ọnụ maka ụbọchị 28. N'agbanyeghị na ọ dị mma na toltrazuril, ojiji ya ebelatala n'ịnyịnya n'ihi na enwere ọgwụ ndị ọzọ dị irè nke ọma.
