Nkọwa dị mkpirikpi:
Nọmba CAS: 24390-14-5
Usoro ihe omimi: C24H31ClN2O9
arọ molekụla: 526.97
Ọdịdị kemịkal:
| Ozi bụ isi | |
| Aha ngwaahịa | Doxycycline hyclate |
| Ọkwa | ọkwa ọgwụ |
| Ọdịdị | odo, hygroscopic crystalline ntụ ntụ |
| Nyocha | 99% |
| Ndụ nchekwa | afọ 2 |
| Nkwakọ ngwaahịa | 25kg / katọn |
| Ọnọdụ | echekwara na jụụ na nkụ |
Nkọwa nke Doxycycline Hyclate
Doxycycline bụ onye so na tetracycline ọgwụ nje, a na-ejikarị agwọ ọrịa dị iche iche. dissolves na ngwọta nke alkali hydroxides na carbonates.
Doxycycline Hyclate bụ ụdị nnu hyclate nke doxycycline, bụ ọgwụ nje tetracycline sara mbara. Ọ na-egbochi njikọ protein nke nje site na ijikọ ribosomes. Doxycycline na-ahọrọkwa matriks mmadụ metalloproteinase-8 (MMP-8) na MMP-13 karịa MMP-1 na mgbochi 50, 60 na 5%, n'otu n'otu, mgbe ejiri ya na ntinye nke 30 μM. Enwere ike iji ya dị ka onye na-achịkwa maka usoro okwu mkpụrụ ndụ inducible ebe okwu dabere na ọnụnọ (Tet-On) ma ọ bụ enweghị (Tet-Off) nke doxycycline. A na-eji usoro ndị nwere doxycycline mee ihe n'ịgwọ ọrịa nje na igbochi ịba.
Ojiji nke Doxycycline hyclate
Doxycycline hyclate bụ otu n'ime otu ọgwụ nje tetracycline, a na-ejikarị agwọ ọrịa dị iche iche. A na-eji ya na ọgwụgwọ chlamydia, rickettsia, mycoplasma na ụfọdụ ọrịa spirochete. A na-ejikwa ya egbochi matrix metalloproteinases na doses subantimicrobial. Na-egbochi matriks metalloproteinases na doses subantimicrobial.
Doxycycline hyclate bụ ihe na-emepụta oxytetracycline sịntetik. A na-eji ya kpochapụ Borrelia burgdorferi na Anaplasma phagocytophilum na mmiri mmiri na-ekpochapụ Ixodes scapularis akọrọ. Ọ bụ ihe mgbochi dị iche iche nke a na-eji egbochi matrix metalloproteinases (MMP), dị ka ụdị 1 collagenase na ọmụmụ banyere ọgwụgwọ ọnya na nhazigharị anụ ahụ.
