Nkọwa dị mkpirikpi:
Nọmba CAS: 126-07-8
Usoro ihe omimi: C17H17ClO6
arọ molekụla: 352.77
Ọdịdị kemịkal:
| Ozi bụ isi | |
| Aha ngwaahịa | Griseofulvin |
| Ọkwa | ọkwa ọgwụ |
| Ọdịdị | Ọcha ka odo-acha ọcha ntụ ntụ |
| Nyocha | 99% |
| Ndụ nchekwa | afọ 2 |
| Nkwakọ ngwaahịa | 25kg / katọn |
| Njirimara | Nke a na-adịghị ahụkebe na mmiri, na-agbaze kpamkpam na dimethylformamide na tetrachloroethane, soluble ntakịrị na ethanol anhydrous na methanol. |
| Ọnọdụ | Debe akpa ahụ n'ebe kpọrọ nkụ, ebe ikuku na-ekpo ọkụ. |
Nkọwa mkpokọta nke Griseofulvin
Griseofulvin bụ ọgwụ mgbochi fungal na-abụghị polyene;ọ nwere ike igbochi mitosis nke cell fungal ma gbochie njikọ DNA fungal;ọ nwekwara ike jikọta na tubulin iji gbochie nkewa mkpụrụ ndụ fungal.A na-etinye ya na ọgwụgwọ ụlọ ọgwụ kemgbe 1958 ma ugbu a ejirila ya mee ihe maka ịgwọ ọrịa fungal nke akpụkpọ ahụ na stratum corneum na mmetụta inhibitory siri ike na Trichophyton rubrum na Trichophyton tonsorans, wdg. ọgwụgwọ nke ọrịa fungal nke akpụkpọ anụ na cuticle, ma tinyekwa ya n'ọrụ ugbo maka mgbochi na ọgwụgwọ nke ọrịa fungal;dịka ọmụmaatụ, ọ nwere mmetụta pụrụ iche n'ịgwọ ụdị candidiasis na apụl nke nwere ike ibute ọrịa n'oge pollination.
Ngosipụta nke Griseofulvin
Na ọgwụ,Ngwaahịa a dabara adaba maka ọgwụgwọ ụdị mgbanaka dị iche iche, gụnyere tinea capitis, tinea barbae, tinea body, jock itch, tinea ụkwụ na onychomycosis.Ụdị tinea dị iche iche a kpọtụrụ aha bụ nke fungi dị iche iche gụnyere Trichophyton rubrum, Trichophyton tonsorans, Trichophyton mentagrophytes, Fingers Trichophyton, wdg, na Microsporon audouini, Microsporon canis, Microsporon gypseum na Epidermophyton floccosum, wdg n'ihi.Ngwaahịa a adabaghị maka ọgwụgwọ n'ọnọdụ dị nro, ọrịa ọrịa mpaghara yana ikpe nke enwere ike ịgwọ ya na ọgwụ antifungal.Griseofulvin adịghị arụ ọrụ n'ịgwọ ọrịa nke ụdị fungi dị iche iche dị ka Candida, Histoplasma, Actinomyces, ụdị Sporothrix, Blastomyces, Coccidioides, Nocardio na Cryptococcus yana ịgwọ tinea versicolor.
N'ọrụ ugbo,Brian etal (1951) bu ụzọ weba ngwaahịa a maka njikwa ọrịa osisi.Dị ka ọmụmụ gara aga, ọ ga-eji maka mgbochi nke egusi ( egusi) vine blight, mgbape mgbasa ọrịa, anyụ blight, anthracnose, apple ifuru ire ere, apụl oyi ire ere, apụl ire ere, kukumba downy mildew , strawberry isi awọ ebu, gourds nghọta blight. , powdery mildew nke Roses, chrysanthemums powdery mildew, ire ere letus, mmalite tomato blight, tulip ọkụ blight na ndị ọzọ fungal ọrịa.
