Nkọwa dị mkpirikpi:
Nọmba CAS: 50-78-2
Usoro ihe omimi:C9H8O4
arọ molekụla: 180.16
Ọdịdị kemịkal:
| Ozi bụ isi | |
| Aha ndị ọzọ | Acetylsalicylic acid |
| Aha ngwaahịa | Aspirin |
| Ọkwa | Ọkwa Pharma/Nri nri |
| Ọdịdị | White crystalline ntụ ntụ |
| Nyocha | 99% |
| Ndụ nchekwa | afọ 2 |
| Njirimara | Na-agbaze ntakịrị na mmiri, soluble na ethanol, ethyl ether, chloroform, sodium hydroxide solution na sodium carbonate solution. |
| Nchekwa | Debe ebe dị jụụ |
Nkọwa ngwaahịa
Aspirin, nke a makwaara dị ka acetylsalicylic acid (ASA), bụ ọgwụ a na-eji ebelata mgbu, ahụ ọkụ, ma ọ bụ mbufụt. Ọnọdụ mkpali akọwapụtara nke aspirin na-agwọ gụnyere ọrịa Kawasaki, pericarditis, na ahụ ọkụ rheumatic.Aspirin bụ ọgwụ a na-ejikarị eme ihe n'ụwa niile.
Ọrụ
Acetylsalicylic acid nwere antipyretic analgesic, mgbochi mkpali na mgbochi rheumatism mmetụta, ya mere a na-ejikarị ya maka ahụ ọkụ, isi ọwụwa, ahụ mgbu, neuralgia, rheumatic ahụ ọkụ, nnukwu rheumatic ogbu na nkwonkwo, gout, wdg;ọ nwekwara mmetụta nchịkọta antiplatelet, enwere ike iji ya mee ihe maka mgbochi nke thrombosis arterial, atherosclerosis, ischemia cerebral na-agafe agafe na infarction myocardial;na mgbakwunye, acetylsalicylic acid nwekwara ike iji na ọgwụgwọ nke biliary tract ọrịa roundworm na ụkwụ egwuregwu.
Omume ọgwụ
Acetylsalicylic acid bụ otu n'ime ọgwụ analgesics antipyretic ọdịnala, yana ọrụ nchịkọta platelet.Acetylsalicylic acid n'ime ahụ nwere njirimara nke antithrombotic, nwere ike belata nguzobe nke mgbochi ọbara na akwara ndị gbara ya gburugburu, na-egbochi ntọhapụ nke nzaghachi platelet na endogenous ADP, 5-HT, wdg, yabụ na-egbochi usoro nke abụọ karịa nke mbụ. usoro nke nchịkọta platelet.Usoro nke acetylsalicylic acid bụ ime ka platelet cyclooxygenase acetylation, si otú a na-egbochi guzobe peroxide mgbanaka, na TXA2 guzobe na-ebelatakwa.Ka ọ dị ugbu a na-eme ka platelet membrane protein acetylation, na-egbochi platelet membrane enzyme, nke na-enyere aka igbochi ọrụ platelet.Ka a na-egbochi cyclooxygenase, ọ na-emetụta mgbidi arịa ọbara nke emebere ka ọ bụrụ PGI2, a ga-egbochikwa platelet TXA2 synthetic enzymes;yabụ ọ ga-emetụta nhazi nke ma TXA2 na PGI2 mgbe ọ bụ nnukwu doses.Kwesịrị ekwesị maka ọrịa obi ischemic, mgbe transluminal coronary angioplasty ma ọ bụ akwara akwara gafere grafting, na-egbochi ọrịa strok na-adịru nwa oge, infarction myocardial ma belata arrhythmia.A nwekwara ike iji Acetylsalicylic acid na ọgwụgwọ ọrịa biliary tract roundworm na ụkwụ ndị na-eme egwuregwu.
Ngwa
Ọ bụ nke mbụ etinyere, nke kachasị ewu ewu na nke a na-ahụkarị antipyretic analgesics anti-rheumatism ọgwụ, nwere akụkụ nke ọgwụ mmetụta dị ka antipyretic-analgesic na mgbochi mkpali, mgbochi platelet aggregation na-arụ ọrụ ngwa ngwa na n'ụzọ dị irè.Enwere ike ịchọpụta ọgwụ ị theụbiga mmanya ókè n'ụzọ dị mfe ma gwọọ ya, yana mmeghachi ahụ nfụkasị ahụ na-adịghị ahụkebe.A na-ejikarị ahụ ọkụ oyi, isi ọwụwa, neuralgia, nkwonkwo mgbu, mgbu anụ ahụ, ahụ ọkụ rheumatic, nnukwu ọrịa ogbu na nkwonkwo mmekọahụ, ọrịa ogbu na nkwonkwo na eze mgbu, wdg Edepụtara na National Essential Medicine List.Acetylsalicylic acid na-arụkwa ọrụ dị ka onye n'etiti ọgwụ ndị ọzọ.
